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Home > Products >  Bicalutamide USP Grade 98%min

Bicalutamide USP Grade 98%min CAS NO.90357-06-5

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  • Min.Order: 1 Gram
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Keywords

  • Bicalutamide
  • 90357-06-5
  • Bicalutamide USP Grade

Quick Details

  • ProName: Bicalutamide USP Grade 98%min
  • CasNo: 90357-06-5
  • Molecular Formula: C18H14F4N2O4S
  • Appearance: white or almost white crystal powder
  • Application: Prostate drug
  • DeliveryTime: ASAP
  • PackAge: 25kgs cardboard drum
  • Port: Shanghai, Qindao or as client's requir...
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: 99%
  • Storage: Cool, dry, shading, and sealed storage...
  • Transportation: Express, air or sea
  • LimitNum: 1 Gram
  • Residue on Ignition: NMT 0.1%
  • Heavy Metal: NMT 100ppm
  • Valid Period: 3 years

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Details

Bicalutimide
CAS RN: 90357-06-5
Chemical name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxyl-2- methylpropanemide
Synonyms: Bicalutamide (Subject to patent free); 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamid; [(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide ; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
 
Molecular formula:C18H14F4N2O4S
molecular weight: 430.38
 
Characters: It’s a white or almost white crystal powder, odorless, tasteless, freely soluble in DMF; Soluble in butylene oxide; sparingly soluble in acetic ether and methanol; insoluble in water. 
 
Quality Standard: EP9.0/USP39
 
Specification:
Item Standard
Appearance White to off-white powder
Solubility Freely soluble in tetrahydrofuran and acetone; soluble in acetonitrile; sparingly soluble in methanol; slightly soluble in alcohol.
Identification
A: infrared spectrum   Infrared absorption spectrohotometry confirm
B: hplc The sample spectrum corresponds to standard
Specific optical rotation +25.0° ~+27.5°
Residue on Ignition NMT 0.1%
Heavy metals NMT 10ppm
Water NMT 0.2%
Organic impurities NMT 0.1%
Bicalutamide aminobenzonitrile NMT 0.1%
Bicalutamide relate compound A isomer A NMT 0.1%
Bicalutamide relate compound A isomer B NMT 0.1%
Desfluoro bicalutamide NMT 0.2%
2-Fluoro bicalutamide NMT 0.2%
Deoxybicalutamide NMT 0.2%
Bicalutamide sulfide NMT 0.1%
Any unspecified impurity NMT 0.1%
Total impurities NMT 0.5%
Residual Solvent DMAC≤1090ppm
Ethanol≤1000ppm
Dichloromethane≤300ppm
Ethyl acetate≤1000ppm
MIBK≤1000ppm
Petroleum ether≤1000ppm
Benzene≤2ppm
Assay 98.0%-102.0%
Usage:
Prostate drug, It is developed by AstraZenca Internatioal,and it is the first antiandrogen non-corticosteroids drug for long-acting oral medication and firstly go on the market in 1995 in UK. An antiandrogen non-corticosteroids can be used treating prostate cancer in advanced stage as assistant drug, may also for treating prostate cancer in the early stage to play an important role.
 
Storage:
It should be kept in room temperature, and away from light; stored in sealed containers.
 
Packing: paper bucket, 25kg/package.

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